Laboratory of Regulatory Systems Neuroscience

                       
              Leptin receptors in the NTS localized to the medial subnucleus with PSTAT3 immunohistochemistry*                            Gastric distension stimulates 40% of leptin receptor positive medial NTS neurons*
                                                                                                                                                                                                                                                                    *Huo L, Maeng L, Bjorbaek C, Grill HJ

What controls how much we eat and how much we weigh?  The answers to these simple questions are still largely obscure.  An understanding of the basic processes underlying ingestion control requires attention to metabolism, hormonal signals, feedback from the gut, and most importantly, identification of the brain circuits and their neurochemical signatures.  Finally, insights can be derived from the structure of feeding behavior itself.  Work in our laboratory proceeds on all of these fronts. 

Last updated 4/03/07
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